你好Bio/Latrunculin A/HB0375/100μg
商品编号：
HB0375-100μg
品牌：
hellobio
市场价：
¥1677.00
美元价：
1290.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameLatrunculinA
- ShortdescriptionActinpolymerizationinhibitor
- BIOLOGicaldescriptionActinpolymerizationinhibitorthatbindstomonomericGactin(Kd=0.2µM).Alsoinhibitsadeninenucleotideexchangeonactin.PlaysaroleindepolymerizationoftumorcellCytoskeletonandshowspossIBLeanti-inflammatoryproperties.
- BiologicalactionInhibitor
- Purity>96%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxABIcyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone
- MolecularWeight421.55
- Chemicalstructure
![Latrunculin A [76343-93-6]](images/hellobio/201710/hb0375.png "Latrunculin A [76343-93-6]")
- MolecularFormulaC22H31NO5S
- CASNumber76343-93-6
- PubChemidentifier445420
- SMILESC[C@H]/1CC[C@@H]2C[C@H](C[C@@](O2)([C@@H]3CSC(=O)N3)O)OC(=O)/C=C(CC/C=C/C=C1)/C
- InChiInChI=1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3+,7-5-,16-11-/t15-,17-,18-,19+,22-/m1/s1
- InChiKeyDDVBPZROPPMBLW-IZGXTMSKSA-N
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewSolubleinDMSO(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforLatrunculinA
Actin-latrunculinAstructureandfunction.Differentialmodulationofactin-bindingproteinfunctionbylatrunculinA.
YarmolaEGetal(2000)JBiolChem275(36):28120-7.PubMedID:10859320Characterizationoftheactivitiesofactin-affectingdrugsontumorcellmigration.
HayotCetal(2006)ToxicolApplPharmacol211(1):30-40.PubMedID:16005926InhibitionofactinpolymerizationbylatrunculinA.
CouéMetal(1987)FEBSLett213(2):316-8.PubMedID:3556584
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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