Hello Bio/JX 401/HB1298/50mg
商品编号：
HB1298-50mg
品牌：
hellobio
市场价：
¥8034.00
美元价：
6180.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameJX 401
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Short descriptionPotent, reversible p38α MAPK inhibitor
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Biological descriptionPotent and reversible p38α MAPK inhibitor (IC50 = 32 nM) that isn't ATP-competitive. Membrane permeable. Exhibits little or no activity at p38γ. Inhibits Elk1 phosphorylation. Displays anti-inflmmatory properties.
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Biological actionInhibitor
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Purity>98%
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Our products in actionSubmit Your Citation Now
Properties
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Chemical name1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine
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Molecular Weight355.49
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Molecular FormulaC21H25NO2S
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CAS Number349087-34-9
Storing and Using Your Product
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Storage instructionsroom temperature
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Solubility overviewsoluble in DMSO (75mM) or ethsnol (50mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for JX 401
JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast.
Friedmann Y et al (2006) Mol Pharmacol 70(4) : 1395-405.PubMedID: 16847144
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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