Hello Bio/(-)-Huperzine A/HB0001/50mg
商品编号：
HB0001-50mg
品牌：
hellobio
市场价：
¥10042.50
美元价：
7725.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name(-)-HuperzineA
- ShortdescriptionAChEinhibitor/NMDAreceptorantagoNIST
- BIOLOGicaldescriptionAcetylcholinesteraseinhibitor(Ki=6.2nM).AlsoNMDAreceptorantagonist(Ki=6μMatPCPsite).Bloodbrainbarrierpermeable.Promoteshippocampalneurogenesis.Displayspotentantinociceptiveandanticonvulsantproperties.Alsoshowspositiveeffectsonimprovingcognitiveandbehaviouralfunctions.
- AlternativenamesHupA
- BiologicalactionInhibitor
- Purity>97%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(1R,9S,13E)-1-Amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one
- MolecularWeight242.32
- Chemicalstructure
![(-)-Huperzine A [102518-79-6]](images/hellobio/201710/hb0001.png "(-)-Huperzine A [102518-79-6]")
- MolecularFormulaC15H18N2O
- CASNumber102518-79-6
- PubChemidentifier907504
- SMILESCC=C1C2CC3=C(C1(CC(=C2)C)N)C=CC(=O)N3
StoringandUsingYourProduct
- Storageinstructions+4°C(desiccate)
- SolubilityoverviewsolubleinDMSOorEthanol
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor(-)-HuperzineA
HuperzineApromoteshippocampalneurogenesisinvitroandinvivo.
MaTetal(2013)BrainRes1506:35-43.PubMedID:23454433IntrathecalhuperzineAincreasesthermalescapelatencyanddecreasesflinchingbehaviorintheformalintestinrats.
ParkPetal(2010)NeurosciLett470(1):6-9.PubMedID:20026382TheNMDAreceptorionchannel:asiteforbindingofHuperzineA.
GordonRKetal(2001)JApplToxicol21Suppl1:S47-51.PubMedID:11920920IdentificationofaminoacidresiduesinvolvedinthebindingofHuperzineAtocholinesterases.
SaxenaAetal(1994)ProteinSci3(10):1770-8.PubMedID:7849595
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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