Hello Bio/12(S)-HPETE/HB0060/100μg
商品编号：
HB0060-100μg
品牌：
hellobio
市场价：
¥5460.00
美元价：
4200.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name12(S)-HPETE
- ShortdescriptionCaMkinaseIIinhibitor
- BIOLOGicaldescriptionEndogenousCAMKIIinhibitor.Showsmanybiologicalactions.Suppressesplateletcyclooxygenasetosuppressthromboxaneandinhibitsplateletactivation.Showsneurotoxicactions.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname12S-hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoicacid
- MolecularWeight336.5
- Chemicalstructure
![12(S)-HPETE [71774-10-2]](images/hellobio/201710/hb0060.png "12(S)-HPETE [71774-10-2]")
- MolecularFormulaC20H32O4
- CASNumber71774-10-2
- PubChemidentifier656507
- SMILESCCCCCC=CCC(C=CC=CCC=CCCCC(=O)O)OO
StoringandUsingYourProduct
- Solubilityoverviewsolubleinwater(0.8mg/ml,at25oC)orDMSO
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor12(S)-HPETE
12-hydroperoxyeicosatetraenoicacidinhibitsmainplateletfunctionsbyactivationofsolubleguanylatecyclase.
BrüneBetal(1991)MolPharmacol39(5):671-8.PubMedID:1674588Inhibitionofreninreleasebyarachidonicacidmetabolites,12(s)-HPETEand12-HETE:roleofTRPV1channels.
XieCetal(2011)Endocrinology152(10):3811-9.PubMedID:21846804InteractionsbetweenCB(1)receptorsandTRPV1channelsmediatedby12-HPETEarecytotoxictomesencephalicdopaminergicneurons.
KimSRetal(2008)BrJPharmacol155(2):253-64.PubMedID:18552868
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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