Hello Bio/Herbimycin A/HB1325/500μg
商品编号：
HB1325-500μg
品牌：
hellobio
市场价：
¥6922.50
美元价：
5325.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameHerbimycinA
- ShortdescriptionSrcfamilykinaseinhibitor
- BIOLOGicaldescriptionSrcfamilykinaseinhibitor.InhibitsHsp90intheheatshockresponse.InhibitsIκBkinaseβandsuppressesNF-κB.Showsanti-inflammatory,antibioticandanti-angiogenicactions.
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(15R)-17-demethoxy-15-methoxy-11-O-methyl-geldanamycin
- MolecularWeight574.67
- MolecularFormulaC30H42N2O9
- CASNumber70563-58-5
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewsolubleinDMSO(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforHerbimycinA
HerbimycinAinhibitsangiogenicactivityinendothelialcellsandreducesneovascularizationinaratmodelofretinopathyofprematurity.
McCollumGWetal(2004)ExpEyeRes78(5):987-95.PubMedID:15051479HerbimycinAabrogatesnuclearfactor-kappaBactivationbyinteractingpreferentiallywiththeIkappaBkinasebetasubunit.
OginoSetal(2004)MolPharmacol65(6):1344-51.PubMedID:15155828InhibitionofHsp90functiondelaysandimpairsrecoveryfromheatshock.
DuncanRF(2005)FEBSJ272(20):5244-56.PubMedID:16218955
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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