你好生物/棉酚/HB0304/500mg
商品编号：
HB0304-500mg
品牌：
hellobio
市场价：
¥6435.00
美元价：
4950.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameGossypol
- ShortdescriptionDehydrogenaseenzymeinhibitor
- BIOLOGicaldescriptionDehydrogenaseenzymeinhibitor.Bcl-2homology3(BH3)-mimeticagent,bindstotheBH3domainofmembersoftheB-celllymphoma2(Bcl-2)family.InhibitsAPE-1(apurinic/apyrimidinicendonuclease1)activity.Showsantioxidant,antiviral,antiparasitic,apoptoticandanticanceractions.
- BiologicalactionInhibitor
- Purity>90%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnamePogosin;AT101
- MolecularWeight518.56
- Chemicalstructure
![Gossypol [303-45-7]](images/hellobio/201710/hb0304.png "Gossypol [303-45-7]")
- MolecularFormulaC30H30O8
- CASNumber303-45-7
- PubChemidentifier3503
- SMILESCC1=C(C(=C2C(=C1)C(=C(C(=C2C=O)O)O)C(C)C)O)C3=C(C=C4C(=C3O)C(=C(C(=C4C(C)C)O)O)C=O)C
StoringandUsingYourProduct
- Solubilityoverviewsolubleinethanol(25mg/ml)orDMF(25mg/ml)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforGossypol
IdentificationofanovelpotentialantitumoractivityofgossypolasanAPE1/Ref-1inhibitor.
QianCetal(2014)DrugDesDevelTher8:485-96.PubMedID:24872679Gossypol:acontraceptiveformen.
CoutinhoEM(2002)Contraception65(4):259-63.PubMedID:12020773Gossypol:prototypeofinhibitorstargetedtodinucleotidefolds.
VanderJagtDLetal(2000)CurrMedChem7(4):479-98.PubMedID:10702620Therapeuticpotentialofgossypol:anoverview.
Keshmiri-NeghabHetal(2014)PharmBiol52(1):124-8.PubMedID:24073600
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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