Hello Bio/GABA/HB0882/
市场价：
¥1345.50
美元价：
1035.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameGABA
- ShortdescriptionEndogenousinhibitoryneurotransmitter
- BIOLOGicaldescription
Mainendogenousinhibitoryneurotransmitter.ActivatesionotropicGABAAandGABAA-ρreceptorsandmetabotropicGABABreceptors.Alsoinducesα-cell-mediatedβ-likeendocrinecellneogenesisinvivo.
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname4-Aminobutyricacid
- MolecularWeight103.12
- Chemicalstructure
![GABA [56-12-2]](images/hellobio/201710/hb0882.png "GABA [56-12-2]")
- MolecularFormulaC4H9NO2
- CASNumber56-12-2
- PubChemidentifier119
- SMILESC(CC(=O)O)CN
- InChiInChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
- InChiKeyBTCSSZJGUNDROE-UHFFFAOYSA-N
- MDLnumberMFCD00008226
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforGABA
GABAcreceptors:relativelysimpletransmitter-gatedionchannels?
JohnstonGA(1996)TrendsPharmacolSci17(9):319-23.PubMedID:8885697GABAandGABAreceptorsinthecentralnervoussystemandotherorgans.
WatanabeMetal(2002)IntRevCytol213:1-47.PubMedID:11837891GABA:adominantneurotransmitterinthehypothalamus.
DecavelCetal(1990)JCompNeurol302(4):1019-37.PubMedID:2081813SynthesisofneurotransmitterGABAviatheneuronaltricarboxylicacidcycleiselevatedinratswithlivercirrhosisconsistentwithahighGABAergictoneinchronichepaticencephalopathy.
LekeRetal(2011)JNeuRochem117(5):824-32.PubMedID:21395584Long-TermGABAAdmiNISTrationInducesAlphaCell-MediatedBeta-likeCellNeogenesis.
Ben-Othmanetal(2017)Cell.168(1-2)::73-85PubMedID:27916274
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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