你好Bio/FPA 124/HB1249/50mg
市场价：
¥9301.50
美元价：
7155.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameFPA124
- ShortdescriptionAktinhibitor
- BIOLOGicaldescriptionAkt(PKB)inhibitor(IC50=100nM).InactivatesNF-κB.Showsanti-proliferativeactions.
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameDichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamidecoppercomplex
- MolecularWeight381.73
- Chemicalstructure
![FPA 124 [902779-59-3]](images/hellobio/201710/hb1249.png "FPA 124 [902779-59-3]")
- MolecularFormulaC11H9Cl2CuN3O2S
- CASNumber902779-59-3
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(10mM)orethanol(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforFPA124
Synthesis,molecularcharacterization,andbiologicalactivityofnovelsyntheticderivativesofchromen-4-oneinhumancancercells.
BarveVetal(2006)JMedChem49(13):3800-8.PubMedID:16789737ActivationofproteinkinaseB/Aktbyalpha1-adrenoceptorsinthehumanprostate.
StrittmatterFetal(2012)LifeSci90(11-12):446-53.PubMedID:22280833
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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