
你好Bio/马来酸氟伏沙明/HB2138/10mg
商品编号:
HB2138-10mg
品牌:
hellobio
市场价:
¥702.00
美元价:
540.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product overview
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NameFluvoxamine maleate
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Short descriptionSelective serotonin reuptake inhibitor and σ1 receptor agonist
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Biological descriptionSelective serotonin reuptake inhibitor and σ1 receptor agonist (Ki = 36 nM at σ1). Shows antidepressant and anxiolytic activity. Active in vivo.
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Alternative namesNSC 309469
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Biological actionInhibitor
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Purity>98%
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Our products in actionSubmit Your Citation Now
Properties
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Chemical name(E)-5-Methoxy-1-[4-(trifluoromethyl )phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate
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Molecular Weight434.41
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Chemical structure
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Molecular FormulaC15H21F3N2O2.C4H4O4
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CAS Number61718-82-9
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PubChem identifier9560989
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SMILESCOCCCC/C(=NOCCN)/C1=CC=C(C=C1)C(F)(F)F.C(=CC(=O)O)C(=O)O
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InChiInChI=1S/C15H21F3N2O2.C4H4O4/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18;5-3(6)1-2-4(7)8/h5-8H,2-4,9-11,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b20-14+;2-1-
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InChiKeyLFMYNZPAVPMEGP-PIDGMYBPSA-N
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MDL numberMFCD00269809
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AppearanceWhite solid
Storing and Using Your Product
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Storage instructions+4°C (desiccate)
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Solubility overviewSoluble in water (10mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Fluvoxamine maleate
Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor.
Claassen et al (1977) Br J Pharmacol 60(4) : 505-16PubMedID: 302726Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain.
Narita et al (1996) Eur J Pharmacol 307(1) : 117-9PubMedID: 8831113Fluvoxamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness.
Benfield (1986) Drugs 32(4) : 313-34PubMedID: 3096686
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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