Hello Bio/Felodipine/HB1222/100mg
商品编号：
HB1222-100mg
品牌：
hellobio
市场价：
¥10354.50
美元价：
7965.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameFelodipine
- ShortdescriptionSelectiveL-typeVOCCblocker
- BIOLOGicaldescriptionSelectiveL-typevoltage-operatedcalciumchannel(VOCC)blocker(pIC50=8.30mM).ExhibitsselectivityforL-typechannelsoverL-,N-,P/Q-,andR-typechannels.Displaysvascularrelaxant,vascularprotective,antihypertensiveandantianginalproperties.
- BiologicalactionBlocker
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylicacidethylmethylester
- MolecularWeight384.25
- Chemicalstructure
![Felodipine [72509-76-3]](images/hellobio/201710/hb1222.png "Felodipine [72509-76-3]")
- MolecularFormulaC18H19Cl2NO4
- CASNumber72509-76-3
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforFelodipine
QuantitativeanalysisofvasculartocardiacselectivityofL-andT-typevoltage-operatedcalciumchannelantagoNISTsinhumantissues.
AngusJAetal(2000)ClinExpPharmacolPhysiol27(12):1019-21.PubMedID:11117223Felodipineinhibitsfree-rADIcalproductionbycytokinesandglucoseinhumansmoothmusclecells.
HishikawaKetal(1998)Hypertension32(6):1011-5.PubMedID:9856965SelectivitiesofdihydropyridinederivativesinblockingCa(2+)channelsubtypesexpressedinXenopusoocytes.
FurukawaTetal(1999)JPharmacolExpTher291(2):464-73.PubMedID:10525060HumanvasculartocardiactissueselectivityofL-andT-typecalciumchannelantagonists.
SarSERODetal(1998)BrJPharmacol125(1):109-19.PubMedID:9776350
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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