Hello Bio/Evans blue/HB0280/1g
市场价：
¥526.50
美元价：
405.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameEvansblue
- ShortdescriptionPotentAMPA/kainatereceptorantagoNIST.VesicularL-glutamateuptakeinhibitor.
- BIOLOGicaldescriptionPotentAMPAandkainatereceptorantagonist(IC50valuesare150and220nMforGluK2andGluA1respectively).VesicularL-glutamateuptakeinhibitor..AlsoselectiveP2X-purinoceptorantagonist.Usedasadye.
- BiologicalactionDyes&stains
- Purity>95%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname6,6-[(3,3"-Dimethyl[1,1"-biphenyl]-4,4"-diyl)bis(azo)bis[4-amino-5-hydroxy-1,3-naphthalenedisulphonicacid]tetrasodiumsalt
- MolecularWeight960.82
- Chemicalstructure
![Evans blue [314-13-6]](images/hellobio/201710/hb0280.png "Evans blue [314-13-6]")
- MolecularFormulaC34H24N6Na4O14S4
- CASNumber314-13-6
- PubChemidentifier9566057
- SMILESO=S(=O)(O[Na])c6cc(c(N)c5c6ccc(/N=N/c1ccc(cc1C)c4ccc(/N=N/c3ccc2c(cc(c(N)c2c3O)S(=O)(=O)O[Na])S(=O)(=O)O[Na])c(C)c4)c5O)S(=O)(=O)O[Na]
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- Solubilityoverviewsolubleinwater(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforEvansblue
UptakeofL-glutamateintosynapticvesicles:competitiveinhibitionbydyeswithbiphenylandamino-andsulphonicacid-substitutednaphthylgroups.
RosethSetal(1998)BiochemPharmacol56(9):1243-9.PubMedID:9802337P2-purinoceptorantagonists:II.BlockadeofP2-purinoceptorsubtypesandecto-nucleotidasesbycompoundsrelatedtoEvansblueandtrypanblue.
WittenburgHetal(1996)NaunynSchmiedebergsArchPharmacol354(4):491-7.PubMedID:8897453Evansblueantagonizesbothalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionateandkainatereceptorsandmodulatesreceptordesensitization.
PriceCJetal(1996)MolPharmacol50(6):1665-71.PubMedID:8967991DifferentialmodulationofAMPAreceptormediatedcurrentsbyevansblueinpostnatalrathippocampalneurones.
SchürmannBetal(1997)BrJPharmacol121(2):237-47.PubMedID:9154333
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
