Hello Bio/D-erythro-Sphingosine/HB0239/50mg
商品编号：
HB0239-50mg
品牌：
hellobio
市场价：
¥3646.50
美元价：
2805.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameD-erythro-Sphingosine
- ShortdescriptionPKCinhibitor
- BIOLOGicaldescriptionProteinkinaseC(PKC)inhibitor.AlsoTRPM3channelactivator(EC50=12µM).ExhibitslittleornoactivityforotherTRPchannels.Alsoinhibitsplateletaggregation.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameSphingosine,C18chain
- MolecularWeight299.5
- MolecularFormulaC18H37NO2
- CASNumber123-78-4
- PubChemidentifier5280335
- SMILESCCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO
StoringandUsingYourProduct
- Solubilityoverviewsolubleinethanol(25mg/ml,gentlewarming)orDMSO(25mg/ml,methanol)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforD-erythro-Sphingosine
AconcisesynthesisofapromisingproteinkinaseCinhibitor:D-erythro-sphingosine.
PhamVTetal(2007)ArchPharmRes30(1):22-7.PubMedID:17328238Activationofthemelastatin-relatedcationchannelTRPM3byD-erythro-sphingosine[corrected].
GrimmCetal(2005)MolPharmacol67(3):798-805.PubMedID:15550678UseofD-erythro-sphingosineasapharmacologicalinhibitorofproteinkinaseCinhumanplatelets.
KhanWAetal(1991)BiochemJ278(Pt2):387-92.PubMedID:1898331
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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