Hello Bio/EHNA hydrochloride/HB3540/25mg
商品编号：
HB3540-25mg
品牌：
hellobio
市场价：
¥2418.00
美元价：
1860.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameEHNAhydrochloride
- ShortdescriptionPotentadenosinedeaminaseandPDE2inhibitor.SupressesspontaneoushESCdifferentiation.
- BIOLOGicaldescriptionPotentadenosinedeaminase(ADA)andPDE2inhibitor(Ki=1.6nMatADAandIC50valuesare0.8and4ΜMathumanandporcinePDE2respectively.ReversIBLysupressesspontaneoushESCsdifferentiation.Alsoactsasastrongblockerofdirectedneuronaldifferentiation.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalnameerythro-9-(2-Hydroxy-3-nonyl)adeninehydrochloride
- MolecularWeight313.83
- Chemicalstructure
![EHNA hydrochloride | [58337-38-5]](images/hellobio/201710/hb3540.png "EHNA hydrochloride | [58337-38-5]")
- MolecularFormulaC14H23N5O.HCl
- CASNumber58337-38-5
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- Solubilityoverviewsolubleinwater(100mM)orDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforEHNAhydrochloride
ProbingtheactivesiteofadenosinedeaminasebyapHresponsivefluorescentcompetitiveinhibitor.
Caiolfaetal(1998)BiophysChem70(1):41-56PubMedID:9474762Erythro-9-(2-hydroxy-3-nonyl)adenine(EHNA)blocksdifferentiationandmaintainstheexpressionofpluripotencyMarkersinhumanembryonicstemcells.
Burtonetal(2010)BiochemJ432(3):575-84PubMedID:20923411Inhibitionofadenosinedeaminasebyerythro-9-(2-hydroxy-3-nonyl)adenine(EHNA)mimicstheeffectofinescapableshockonescapelearninginrats.
Woodsonetal(1998)BehavNeurosci112(2):339-409PubMedID:9588486
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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