Hello Bio/Ebselen/HB0270/25mg
商品编号：
HB0270-25mg
品牌：
hellobio
市场价：
¥1599.00
美元价：
1230.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameEbselen
- ShortdescriptionBroadenzymeinhibitor
- BIOLOGicaldescriptionAntioxidantandanti-inflammatoryagent.InhibitsPKC,NADPH,NADPHoxidase,NOsynthases,5-lipoxygenaseandcyclooxygenase.Mimicsglutathioneperoxidase.Showsneuroprotectiveandanti-canceractions.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname2-Phenyl-1,2-benzisoselenazol-3(2H)-one
- MolecularWeight274.2
- Chemicalstructure
![Ebselen [60940-34-3]](images/hellobio/201710/hb0270.png "Ebselen [60940-34-3]")
- MolecularFormulaC13H9NOSe
- CASNumber60940-34-3
- PubChemidentifier3194
- SMILESC1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
- InChiInChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
- InChiKeyDYEFUKCXAQOFHX-UHFFFAOYSA-N
- MDLnumberMFCD00210937
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforEbselen
Molecularactionsofebselen--anantiinflammatoryantioxidant.
ScheweT(1995)GenPharmacol26(6):1153-69.PubMedID:7590103Studiesontheanti-inflammatoryactivityofebselen.EbseleninterfereswithgranulocyteoxidativeburstbydualinhibitionofNADPHoxidaseandproteinkinaseC?
CotgreaveIAetal(1989)BiochemPharmacol38(4):649-56.PubMedID:2537084Ebselenpretreatmentattenuatesischemia/reperfusioninjuryandpreventshyperglycemiabyimprovinghepaticinsulinsignalingandβ-cellsurvivalingerbils.
ParkSetal(2014)FreeRADIcRes48(8):864-74.PubMedID:24807533Inductionofapoptosisinhumanmultiplemyelomacelllinesbyebselenviaenhancingtheendogenousreactiveoxygenspeciesproduction.
ZhangLetal(2014)BiomedResInt2014:696107PubMedID:24587987
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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