你好生物/DPCPX/HB2094/25mg
商品编号：
HB2094-25mg
品牌：
hellobio
市场价：
¥682.50
美元价：
525.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameDPCPX
- ShortdescriptionPotent,selectiveA1receptorantagoNIST
- BIOLOGicaldescriptionPotentandselectiveA1adenosinereceptorantagonist(Kivaluesare0.45and300nMatA1andA2receptorsrespectively).Activeinvivo.Facilitateslongtermpotentiation(LTP)andblocksinductionoflongtermdepression(LTD).
- BiologicalactionAntagonist
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname8-Cyclopentyl-1,3-dipropylxanthine
- MolecularWeight304.39
- Chemicalstructure
![DPCPX [102146-07-6]](images/hellobio/201710/hb2094_2.png "DPCPX [102146-07-6]")
- MolecularFormulaC16H24N4O2
- CASNumber102146-07-6
- PubChemidentifier1329
- SMILESCCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3CCCC3
- SourceSynthetic
- InChiInChI=1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18)
- InChiKeyFFBDFADSZUINTG-UHFFFAOYSA-N
- MDLnumberMFCD00055117
- AppearanceWhitesolid
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinDMSO(5mM)andinethanol(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforDPCPX
Effectsof1,3-dipropyl-8-cyclopentylxanthine(DPCPX),ahighlyselectiveadenosinereceptorantagonist,onforceofcontractioninguinea-pigatrialandventricularcardiacpreparations.
vonderLeyenetal(1989)NaunynSchmiedebergsArchPharmacol.340(2):204-9PubMedID:25541518-Cyclopentyl-1,3-dipropylxanthine(DPCPX)--aselectivehighaffinityantagonistrADIoligandforA1adenosinereceptors.
Lohseetal(1987)NaunynSchmiedebergsArchPharmacol.336(2):204-10PubMedID:2825043Caffeine,adenosinereceptors,andsynapticplasticity.
Costenlaetal(2010)JAlzheimersDis1:S25-34PubMedID:20182030Activationofreceptorsnegativelycoupledtoadenylatecyclaseisrequiredforinductionoflong-termsynapticdepressionatSchaffercollateral-CA1synapses.
Santschietal(2006)JNeurobiol66(3):205-19PubMedID:16329119
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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