Hello Bio/Dihydrosphingosine/HB0247/10mg
商品编号：
HB0247-10mg
品牌：
hellobio
市场价：
¥1345.50
美元价：
1035.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameDihydrosphingosine
- ShortdescriptionPKCinhibitor
- BIOLOGicaldescriptionProteinkinaseC(PKC)inhibitor.Showsvasodilatoryactions.
- AlternativenamesSphinganine
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameDL-erythro-1,3-Dihydroxy-2-aminooctadecane
- MolecularWeight301.51
- Chemicalstructure
![Dihydrosphingosine [3102-56-5]](images/hellobio/201710/hb0247.png "Dihydrosphingosine [3102-56-5]")
- MolecularFormulaC18H39NO2
- CASNumber3102-56-5
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- SolubilityoverviewsolubleinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforDihydrosphingosine
Effectsofexogenoussphinganine,sphingosine,andsphingosine-1-phosphateonrelaxationandcontractionofporcinethoracicaorticandpulmonaryarterialrings.
HsiaoSHetal(2005)ToxicolSci86(1):194-9.PubMedID:15829618Sphinganinepotentiationofdimethylsulfoxide-inducedgranulocytedifferentiation,increaseofalkalinephosphataseactivityanddecreaseofproteinkinaseCactivityinahumanleukemiacellline(HL-60).
YungBYetal(1994)BiochemBiophysResCommun199(2):888-96.PubMedID:8135836ProteinkinaseCmediatedanti-proliferativeglucocorticoid-sphinganinesynergisminculturedPollardIIIprostatetumorcells.
SosnowskiJetal(1997)JUrol158(1):269-74.PubMedID:9186373
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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