你好Bio/3,4-Dephostatin/HB0072/1mg
市场价：
¥2457.00
美元价：
1890.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name3,4-Dephostatin
- ShortdescriptionProteintyrosinephosphataseinhibitor
- BIOLOGicaldescriptionProteintyrosinephosphataseinhibitor(IC50=18µM).InhibitsSHP-1andsuppressesmyeloiddifferentiationinacutepromyelocyticleukemia.EnhancesneuriteformationinducedbyNGFinPC12hcells.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname3,4-Dihydroxy-N-methyl-N-nitrosoaniline
- MolecularWeight168.15
- Chemicalstructure
- MolecularFormulaC7H8N2O3
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(18mg/ml)orwater
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor3,4-Dephostatin
InhibitionofATRA-inducedmyeloiddifferentiationinacutepromyelocyticleukemiabyanewproteintyrosinephosphataseinhibitor,3,4-dephostatin.
UesugiYetal(2000)JExpClinCancerRes19(3):363-6.PubMedID:11144530Enhancementorinductionofneuriteformationbyaproteintyrosinephosphataseinhibitor,3,4-dephostatin,ingrowthfactor-treatedPC12hcells.
FujiwaraSetal(1997)BiochemBiophysResCommun238(1):213-7.PubMedID:9299481Resistancetophorbol12-myristate13-acetate-inducedcellgrowtharrestinanHL60celllinechronicallyexposedtoaglutathioneS-transferasepiinhibitor.
Gatã?Letal(2003)BiochemPharmacol65(10):1611-22.PubMedID:12754097
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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