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商品详细Hello Bio/Dephostatin/HB0236/1mg
Hello Bio/Dephostatin/HB0236/1mg
Hello Bio/Dephostatin/HB0236/1mg
商品编号: HB0236
品牌: hellobio
市场价: ¥2749.50
美元价: 2115.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product overview

  • Name
    Dephostatin
  • Short description
    Competitive PTPase inhibitor
  • Biological description
    Competitive tyrosine phosphatase (PTPase) inhibitor (IC50 = 7.7 µM). Enhances the release of amylase and intracellular calcium. Displays antibacterial and growth inhibition properties.
  • Biological action
    Inhibitor
  • Purity
    >90%
  • Our products in action
    Submit Your Citation Now

Properties

  • Chemical name
    2,5-Dihydroxy-N-methyl-N-nitrosoaniline
  • Molecular Weight
    168.15
  • Chemical structure
    Dephostatin  [151606-30-3]
  • Molecular Formula
    C7H8N2O3
  • CAS Number
    151606-30-3
  • PubChem identifier
    5353574
  • SMILES
    C1(=CC=C(C=C1N(N=O)C)O[H])O[H]

Storing and Using Your Product

  • Solubility overview
    soluble in chloroform or DMSO (22mg/ml)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Dephostatin

  • Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy, isolation, and characterization.

    Imoto M et al (1993) J Antibiot (Tokyo) 46(9) : 1342-6.
    PubMedID: 8226312
  • Effect of dephostatin on intracellular free calcium concentration and amylase secretion in isolated rat pancreatic acinar cells.

    Lajas AI et al (2000) Mol Cell Biochem 205(1-2) : 163-9.
    PubMedID: 10821434
  • Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. II. Structure determination.

    Kakeya H et al (1993) J Antibiot (Tokyo) 46(11) : 1716-9.
    PubMedID: 8270494
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.