Hello Bio/Daphnetin/HB0229/5mg
商品编号：
HB0229-5mg
品牌：
hellobio
市场价：
¥741.00
美元价：
570.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameDaphnetin
- ShortdescriptionProteinkinaseinhibitor
- BIOLOGicaldescriptionProteinkinaseinhibitor(IC50valuesare7.67,9.33and25.01µMatEGFR,PKAandPKCrespectively).Cell-permeable,coumarinderivative.Showsantioxidantandantimalarialactions.
- BiologicalactionInhibitor
- Purity>97%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname7,8-Dihydroxycoumarin
- MolecularWeight178.14
- Chemicalstructure
![Daphnetin [486-35-1]](images/hellobio/201710/hb0229.png "Daphnetin [486-35-1]")
- MolecularFormulaC9H6O4
- CASNumber486-35-1
- PubChemidentifier5280569
- SMILESC1=CC(=C(C2=C1C=CC(=O)O2)O)O
StoringandUsingYourProduct
- SolubilityoverviewsolubleinDMSOorEtOH
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforDaphnetin
Daphnetin,oneofcoumarinderivatives,isaproteinkinaseinhibitor.
YangEBetal(1999)BiochemBiophysResCommun260(3):682-5.PubMedID:10403826Daphnetin,anaturalcoumarinderivative,providestheneuroprotectionagainstglutamate-inducedtoxicityinHT22cellsandischemicbraininjury.
DuGetal(2014)NeuRochemRes39(2):269-75.PubMedID:24343531Daphnetin:anovelantimalarialagentwithinvitroandinvivoactivity.
YangYZetal(1992)AmJTropMedHyg46(1):15-20.PubMedID:1311154
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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