你好，生物/氯氰菊酯/HB0222/1g
市场价：
¥5499.00
美元价：
4230.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameCypermethrin
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Short descriptionPotent PP2B inhibitor
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Biological descriptionPotent phosphatase 2B (PP2B) inhibitor (IC50 = 40 pM). Type II synthetic pyrethroid insecticide. Interacts with sodium channels producing neurotoxin effects. Also potent calcineurin inhibitor (IC50 = 100 nM). Blood brain barrier permeable.
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Biological actionInhibitor
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Purity>96%
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Properties
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Molecular Weight416.3
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Chemical structure
![Cypermethrin [52315-07-8]](images/hellobio/201710/hb0222.png "Cypermethrin [52315-07-8]")
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Molecular FormulaC22H19Cl2NO3
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CAS Number52315-07-8
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PubChem identifier2912
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SMILESCC1(C)C(C=C(/Cl)Cl)C1C(=O)OC(C#N)C1=CC(OC2=CC=CC=C2)=CC=C1
Storing and Using Your Product
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Storage instructions+4°C
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Solubility overviewsoluble in ethanol (25mg/ml) or DMSO
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Cypermethrin
Inhibition of phosphatase 2B prevents expression of hippocampal long-term potentiation.
Wang JH et al (1994) Neuroreport 5(17) : 2377-80.PubMedID: 7881062Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides.
Enan E et al (1992) Biochem Pharmacol 43(8) : 1777-84.PubMedID: 1315545Effect of cypermethrin on memory, movement activity and coordination in mice after transient incomplete cerebral ischemia.
Nieradko-Iwanicka B et al (2008) Pharmacol Rep 60(5) : 699-705.PubMedID: 19066417Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides.
Enan E et al (1992) Biochem Pharmacol 43(8) : 1777-84.PubMedID: 1315545
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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