Hello Bio/Cyclopiazonic acid/HB1117/50mg
商品编号：
HB1117-50mg
品牌：
hellobio
市场价：
¥5245.50
美元价：
4035.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCyclopiazonicacid
- ShortdescriptionPotentSERCA1ainhibitor
- BIOLOGicaldescriptionPotentsarcoplasmicreticulumCa2+-ATPase1a(SERCA1a)inhibitor.Alsoinhibitscellproliferationbutis40timeslesspotentthanochratoxinA(approxIC50=52µM).
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(6aR,11aS,11bR)-rel-10-Acetyl-2,6,6a,7,11a,11b-hexahydro-7,7-dimethyl-9H-pyrrolo[1",2":2,3]isoindolo[4,5,6-cd]indol-9-one
- MolecularWeight336.39
- Chemicalstructure
![Cyclopiazonic acid [18172-33-3]](images/hellobio/201710/hb1117.png "Cyclopiazonic acid [18172-33-3]")
- MolecularFormulaC20H20N2O3
- CASNumber18172-33-3
- PubChemidentifier54682463
- SMILESCC(=O)C1=C([C@@H]2[C@@H]3[C@@H](CC4=C5C3=CNC5=CC=C4)C(N2C1=O)(C)C)O
- InChiInChI=1S/C20H20N2O3/c1-9(23)14-18(24)17-16-11-8-21-13-6-4-5-10(15(11)13)7-12(16)20(2,3)22(17)19(14)25/h4-6,8,12,16-17,21,24H,7H2,1-3H3/t12-,16+,17+/m1/s1
- InChiKeySZINUGQCTHLQAZ-DQYPLSBCSA-N
- MDLnumberMFCD00167445
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewSolubleinethanol(5mM)orDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCyclopiazonicacid
ProbingdeterminantsofcyclopiazonicacidsensitivityofbacterialCa2+-ATPases.
KotšubeiAetal(2013)FEBSJ280(21):5441-9.PubMedID:23621633TheeffectsofthePenicilliummycotoxinscitrinin,cyclopiazonicacid,ochratoxinA,patulin,penicillicacid,androquefortineConinvitroproliferationofporcinelymphocytes.
KeblysMetal(2004)Mycopathologia158(3):317-24.PubMedID:15702270
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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