Hello Bio/Cryptotanshinone/HB1434/100mg
商品编号：
HB1434-100mg
品牌：
hellobio
市场价：
¥6630.00
美元价：
5100.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameCryptotanshinone
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Short descriptionSTAT3 inhibitor
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Biological descriptionSTAT3 inhibitor (IC50 = 4.6 µM). Also inhibits human acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) and SHP2 (IC50 values are 4.09, 6.38 and 22.5 µM respectively). Shows anti-Alzheimer's disease, anticancer, antidiabetic and antiobesity actions.
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Alternative namesCRY; CPT
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Biological actionInhibitor
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Purity>98%
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Our products in actionSubmit Your Citation Now
Properties
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Chemical name1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl[1,2-b]furan-10,11-dione
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Molecular Weight296.36
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Chemical structure
![Cryptotanshinone [35825-57-1]](images/hellobio/201710/hb1434.png "Cryptotanshinone [35825-57-1]")
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Molecular FormulaC19H20O3
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CAS Number35825-57-1
Storing and Using Your Product
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Storage instructionsroom temperature
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Solubility overviewsoluble in DMSO (10mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Cryptotanshinone
Antidiabetes and antiobesity effect of cryptotanshinone via activation of AMP-activated protein kinase.
Kim EJ et al (2007) Mol Pharmacol 72(1) : 62-72.PubMedID: 17429005Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells.
Shin DS et al (2009) Cancer Res 69(1) : 193-202.PubMedID: 19118003Inhibitory effect of cryptotanshinone on angiogenesis and Wnt/β-catenin signaling pathway in human umbilical vein endothelial cells.
Chen Q et al (2014) Chin J Integr Med 20(10) : 743-50.PubMedID: 24740553Cryptotanshinone, an acetylcholinesterase inhibitor from Salvia miltiorrhiza, ameliorates scopolamine-induced amnesia in Morris water maze task.
Wong KK et al (2010) Planta Med 76(3) : 228-34.PubMedID: 19774505
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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