你好生物/隐丹参酮/HB1434/50mg
商品编号：
HB1434-50mg
品牌：
hellobio
市场价：
¥3685.50
美元价：
2835.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCryptotanshinone
- ShortdescriptionSTAT3inhibitor
- BIOLOGicaldescriptionSTAT3inhibitor(IC50=4.6µM).Alsoinhibitshumanacetylcholinesterase(AChE),butyrylcholinesterase(BuChE)andSHP2(IC50valuesare4.09,6.38and22.5µMrespectively).Showsanti-Alzheimer"sdisease,anticancer,antidiabeticandantiobesityactions.
- AlternativenamesCRY;CPT
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl[1,2-b]furan-10,11-dione
- MolecularWeight296.36
- Chemicalstructure
![Cryptotanshinone [35825-57-1]](images/hellobio/201710/hb1434.png "Cryptotanshinone [35825-57-1]")
- MolecularFormulaC19H20O3
- CASNumber35825-57-1
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- SolubilityoverviewsolubleinDMSO(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCryptotanshinone
AntidiabetesandantiobesityeffectofcryptotanshinoneviaactivationofAMP-activatedproteinkinase.
KimEJetal(2007)MolPharmacol72(1):62-72.PubMedID:17429005Cryptotanshinoneinhibitsconstitutivesignaltransducerandactivatoroftranscription3functionthroughblockingthedimerizationinDU145prostatecancercells.
ShinDSetal(2009)CancerRes69(1):193-202.PubMedID:19118003InhibitoryeffectofcryptotanshinoneonangiogenesisandWnt/β-cateninsignalingpathwayinhumanumbilicalveinendothelialcells.
ChenQetal(2014)ChinJIntegrMed20(10):743-50.PubMedID:24740553Cryptotanshinone,anacetylcholinesteraseinhibitorfromSalviamiltiorrhiza,amelioratesscopolamine-inducedamnesiainMorriswatermazetask.
WongKKetal(2010)PlantaMed76(3):228-34.PubMedID:19774505
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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