Hello Bio/(R)-CPP/HB0021/50mg
商品编号：
HB0021-50mg
品牌：
hellobio
市场价：
¥13708.50
美元价：
10545.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name(R)-CPP
- ShortdescriptionPotentNMDAreceptorantagoNIST
- BIOLOGicaldescriptionPotentNMDAreceptorantagonist.SelectiveforGluN2AsubtypesoverGluN2B,GluN2CandGluN2Dsubtypes(Kivaluesare41nM,0.27,0.63and1.99μMrespectively).BlocksLTPinduction,inducesglutamatereleaseandcausesattentiondeficitsinrats.
- BiologicalactionAntagonist
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonicacid
- MolecularWeight252.21
- Chemicalstructure
![(R)-CPP [126453-07-4]](images/hellobio/201710/hb0021.png "(R)-CPP [126453-07-4]")
- MolecularFormulaC8H17N2O5P
- CASNumber126453-07-4
- PubChemidentifier6603754
- SMILESC1CN(C[C@@H](N1)C(=O)O)CCCP(=O)(O)O
- InChiInChI=1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15)/t7-/m1/s1
- InChiKeyCUVGUPIVTLGRGI-SSDOTTSWSA-N
- FormulationWhitesolid
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature(desiccate)
- SolubilityoverviewSolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor(R)-CPP
Structure-activityanalysisofanovelNR2C/NR2D-preferringNMDAreceptorantagonist:1-(phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylicacid.
FengBetal(2004)BrJPharmacol141(3):508-16.PubMedID:14718249Long-termpotentiationpromotesproliferation/survivalandneuronaldifferentiationofneuralstem/Progenitorcells.
ChoTetal(2013)PLoSOne8(10):e76860.PubMedID:24146937SertindolerestoresattentionalperformanceandsuppressesglutamatereleaseinducedbytheNMDAreceptorantagonistCPP.
CarliMetal(2011)Psychopharmacology(Berl)214(3):625-37.PubMedID:21049266
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
