你好，Bio/&omega-芋螺毒素MVIIC/HB1219/100μg
商品编号：
HB1219-100μg
品牌：
hellobio
市场价：
¥2203.50
美元价：
1695.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Nameω-ConotoxinMVIIC
- ShortdescriptionN-,P-andQ-typevoltage-dependentCa2+channelblocker
- BIOLOGicaldescriptionCav2.1(P/Q-type)andCav2.2(N-type)voltage-dependentCa2+channelblocker.Peptideneurotoxin.
- BiologicalactionBlocker
- Purity>99%
- SpecialrequirementsAsthisproductisatoxin,customersarerequiredtocompleteashortenduserdeclarationwhenordering.Ourcustomercareteamwillbehappytohelpyouwiththis.
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameH-Cys(1)-Lys-Gly-Lys-Gly-Ala-Pro-Cys(2)-Arg-Lys-Thr-Met-Tyr-Asp-Cys(3)-Cys(1)-Ser-Gly-Ser-Cys(2)-Gly-Arg-Arg-Gly-Lys-Cys(3)-NH2
- MolecularWeight2749
- MolecularFormulaC106H178N40O32S7
- CASNumber147794-23-8
- PubChemidentifier56841670
- SMILESC[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@H]3CSSC[C@H]4C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N4)CO)CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC3=O)CCCNC(=N)N)CCCCN)[C@@H](C)O)CCSC)CC5=CC=C(C=C5)O)CC(=O)O)C(=O)N)CCCCN)CCCNC(=N)N)CCCNC(=N)N
- InChiInChI=1S/C106H178N40O32S7/c1-53-103(178)146-36-15-23-75(146)101(176)144-74-52-185-183-49-71-89(164)126-43-79(154)130-62(21-13-34-120-105(115)116)90(165)133-60(20-12-33-119-104(113)114)87(162)124-42-78(153)129-61(18-6-10-31-109)91(166)140-70(83(112)158)48-
- InChiKeyFHVUTHWUIUXZBY-QLANQDRJSA-N
- MDLnumberMFCD00214640
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- SolubilityoverviewSolubleinwater(1mg/ml)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesforω-ConotoxinMVIIC
Omega-conotoxinMVIICattenuatesneuronalapoptosisinvitroandimprovessignificantrecoveryafterspinalcordinjuryinvivoinrats.
OliveiraKMetal(2014)IntJClinExpPathol7(7):3524-36.PubMedID:25120731Identificationofthreesubunitsofthehighaffinityomega-conotoxinMVIIC-sensitiveCa2+channel.
LiuHetal(1996)JBiolChem271(23):13804-10.PubMedID:8662888Inhibitionofcalciumchannelsinratcentralandperipheralneuronsbyomega-conotoxinMVIIC.
McDonoughetal(1996)JNeurosci16(8):2612-23PubMedID:8786437
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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