Hello Bio/Co 102862/HB1013/10mg
商品编号：
HB1013-10mg
品牌：
hellobio
市场价：
¥1092.00
美元价：
840.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCo102862
- ShortdescriptionPotentvoltage-gatedNa+channelblocker
- BIOLOGicaldescriptionPotentvoltage-gatedNa+channelblocker.Showsgreateraffinityforinactive(Ki=0.4µM)comparedtorestingstateNav1.2channels(Kr=30µM).Showsanticonvulsantandpotentialanalgesicactions.
- BiologicalactionBlocker
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname2-[[4-(4-Fluorophenoxy)phenyl]methylene]hydrazinecarboxamide
- MolecularWeight273.26
- Chemicalstructure
![Co 102862 [181144-66-1]](images/hellobio/201710/hb1013.png "Co 102862 [181144-66-1]")
- MolecularFormulaC14H12FN3O2
- CASNumber181144-66-1
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- SolubilityoverviewsolubleinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCo102862
V102862(Co102862):apotent,broad-spectrumstate-dependentblockerofmammalianvoltage-gatedsodiumchannels.
IlyinVIetal(2005)BrJPharmacol144(6):801-12.PubMedID:15778702Pharmacologyof2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide:apotent,broad-spectrumstate-dependentsodiumchannelblockerfortreatingpainstates.
IlyinVIetal(2006)JPharmacolExpTher318(3):1083-93.PubMedID:16728593FunctionalandpharmacologicalpropertiesofhumanandratNaV1.8channels.
BrowneLEetal(2009)Neuropharmacology56(5):905-14.PubMedID:19371587
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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