Hello Bio/CMIQ/HB0077/1mg
商品编号：
HB0077-1mg
品牌：
hellobio
市场价：
¥4836.00
美元价：
3720.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCMIQ
- ShortdescriptionPotent,selectivePKAinhibitor
- BIOLOGicaldescriptionPotentandselectiveproteinkinaseA(PKA)inhibitor(IC50=30nM).Membranepermeable.BlocksATP-bindingsiteofPKA.Restoresmorphine-relatedbehavioursinmorphinetolerance.
- BiologicalactionInhibitor
- Purity>95%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnamePKAInhibitorXI
- MolecularWeight168.2
- Chemicalstructure
![CMIQ [161468-32-2]](images/hellobio/201710/hb0077.png "CMIQ [161468-32-2]")
- MolecularFormulaC11H8N2
- CASNumber161468-32-2
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(50mg/ml)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCMIQ
PKCandPKAinhibitorsreinstatemorphine-inducedbehaviorsinmorphinetolerantmice.
SmithFLetal(2006)PharmacolRes54(6):474-80.PubMedID:17056270SelectiveinhibitionofcyclicAMP-dependentproteinkinasebyisoquinolinederivatives.
LuZXetal(1996)BiolChemHoppeSeyler377(6):373-84.PubMedID:8839983EpacmediatesacAMP-to-PKCsignalingininflammatorypain:anisolectinB4(+)neuron-specificmechanism.
HuchoTBetal(2005)JNeurosci25(26):6119-26.PubMedID:15987941
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
