Hello Bio/Cilnidipine/HB1217/10mg
商品编号：
HB1217-10mg
品牌：
hellobio
市场价：
¥1852.50
美元价：
1425.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCilnidipine
- ShortdescriptionPotentL-/N-typecalciumchannelblocker
- BIOLOGicaldescriptionPotentL-andN-typecalciumchannelblocker(IC50valuesare100and200nM).InhibitssympatheticneurotransmitterreleaseviaN-typeCa2+channelblock.Showsantihypertensive,cardioprotective,renoprotectiveandneuroprotectiveactions.
- BiologicalactionBlocker
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid2-methoxyethyl(2E)-3-phenyl-2-propenylester
- MolecularWeight492.52
- Chemicalstructure
![Cilnidipine [132203-70-4]](images/hellobio/201710/hb1217.png "Cilnidipine [132203-70-4]")
- MolecularFormulaC27H28N2O7
- CASNumber132203-70-4
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCilnidipine
Cilnidipine:anewgenerationCachannelblockerwithinhibitoryactiononsympatheticneurotransmitterrelease.
TakaharaA(2009)CardiovascTher27(2):124-39.PubMedID:19426250Effectofcilnidipine,anoveldihydropyridineCa++-channelantagoNIST,onN-typeCa++channelinratdorsalrootganglionneurons.
FujiiSetal(1997)JPharmacolExpTher280(3):1184-91.PubMedID:9067302NeuroprotectiveeffectsofadualL/N-typeCa(2+)channelblockercilnidipineintheratfocalbrainischemiamodel.
TakaharaAetal(2004)BiolPharmBull27(9):1388-91.PubMedID:15340224
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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