Hello Bio/CGP 74514A/HB0186/5mg
商品编号：
HB0186-5mg
品牌：
hellobio
市场价：
¥1287.00
美元价：
990.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCGP74514A
- ShortdescriptionSelectiveCDK1inhibitor
- BIOLOGicaldescriptionSelectiveCDK1inhibitor.Showsanti-tumoractivity,inducesapoptosisandmitochondrialdamage.
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname2-N-(2-aminocyclohexyl)-6-N-(3-chlorophenyl)-9-ethylpurine-2,6-diamine
- MolecularWeight385.89
- Chemicalstructure
- MolecularFormulaC19H24ClN7
- PubChemidentifier4644095
- SMILESCCN1C=NC2=C1N=C(N=C2NC3=CC(=CC=C3)Cl)NC4CCCCC4N
StoringandUsingYourProduct
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCGP74514A
InductionofapoptosisinhumanleukemiacellsbytheCDK1inhibitorCGP74514A.
DaiYetal(2002)CellCycle1(2):143-52.PubMedID:12429924ThecytotoxiceffectofemetineandCGP-74514AstudiedwiththehollowfibermodelandArrayScanassayinneuroendocrinetumorsinvitro.
LarssonDEetal(2012)AnticancerAgentsMedChem12(7):783-90.PubMedID:22263790CDK1differentiallyregulatesG-overhanggenerationatleADIng-andlagging-strandtelomeresintelomerase-negativecellsinG2phase.
DaiXetal(2012)CellCycle11(16):3079-86.PubMedID:22871736
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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