Hello Bio/CGP 35348/HB0955/10mg
商品编号：
HB0955-10mg
品牌：
hellobio
市场价：
¥1872.00
美元价：
1440.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCGP35348
- ShortdescriptionSelectiveGABABreceptorantagoNIST
- BIOLOGicaldescriptionSelectiveGABABreceptorantagonist(IC50=34µM).Improveslearningandneuromuscularfunctioninamodelofischemia.Showspro-epilepticactions.Blood-brainbarrierpermeable.
- BiologicalactionAntagonist
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(3-Aminopropyl)(diethoxymethyl)phosphinicacid
- MolecularWeight225.22
- Chemicalstructure
![CGP 35348 [123690-79-9]](images/hellobio/201710/hb0955.png "CGP 35348 [123690-79-9]")
- MolecularFormulaC8H20NO4P
- CASNumber123690-79-9
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- Solubilityoverviewsolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCGP35348
CGP35348:acentrallyactiveblockerofGABABreceptors.
OlpeHRetal(1990)EurJPharmacol187(1):27-38.PubMedID:2176979CGP35348,GABABreceptorantagonist,hasapotentialtoimproveneuromuscularcoordinationandspatiallearninginalbinomousefollowingneonatalbraindamage.
GillaniQetal(2014)BiomedResInt2014:295215PubMedID:24804211InvolvementofGABA(B)receptorsinconvulsant-inducedepileptiformactivityinratneocortexinvitro.
SutorBetal(1998)EurJNeurosci10(11):3417-27.PubMedID:9824455
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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