Hello Bio/CFM-2/HB0179/50mg
商品编号：
HB0179-50mg
品牌：
hellobio
市场价：
¥5206.50
美元价：
4005.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCFM-2
- ShortdescriptionSelective,non-competitiveAMPAreceptorantagoNIST
- BIOLOGicaldescriptionSelectiveandnon-competitiveAMPAreceptorantagonist.InhibitsERK1/2pathwayandactsasanantiproliferativeagent.Alsoshowsanticonvulsantactions.
- BiologicalactionAntagonist
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname1-(4"-Aminophenyl)-3,5-dihydro-7,8-dimethoxy-4H-2,3-benzodiazepin-4-one
- MolecularWeight311.34
- Chemicalstructure
![CFM-2 [178616-26-7]](images/hellobio/201710/hb0179.png "CFM-2 [178616-26-7]")
- MolecularFormulaC17H17N3O3
- CASNumber178616-26-7
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- SolubilityoverviewsolubleinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCFM-2
EffectsofsomeAMPAreceptorantagonistsonthedevelopmentoftoleranceinepilepsy-proneratsandinpentylenetetrazolekindledrats.
DeSarroGetal(1999)EurJPharmacol368(2-3):149-59.PubMedID:10193651AMPAantagonistsinhibittheextracellularsignalregulatedkinasepathwayandsuppresslungcancergrowth.
StepulakAetal(2007)CancerBiolTher6(12):1908-15.PubMedID:180591661-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones:novelAMPAreceptorantagonists.
ChimirriAetal(1997)JMedChem40(8):1258-69.PubMedID:9111300
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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