当前位置：
首页
>
产品中心 >
acid_base_buffer_solution >
Hello Bio/CaM Kinase II (290-309), Calmodulin Antagonist/HB0162/1mg
Hello Bio/CaM Kinase II (290-309), Calmodulin Antagonist/HB0162/1mg
市场价：
¥6162.00
美元价：
4740.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCaMKinaseII(290-309),CalmodulinAntagoNIST
- ShortdescriptionPotent,competitiveCaMKIIinhibitor
- BIOLOGicaldescriptionPotentandcompetitiveCaMKIIinhibitor(IC50=52nM).Actsasapseudosubstrateatthecatalyticcoreoftheenzyme.ReducesCa2+-dependentCl-currentinT84cellsbyapprox.70%,butdoesnotaffectCl-channelsinparotidacinarcells.
- BiologicalactionInhibitor
- Purity>97%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameCa2+/calmodulin-dependentproteinkinaseII(290-309)
- MolecularWeight2273.8
- MolecularFormulaC103H185N31O24S
- CASNumber115044-69-4
- PubChemidentifier22114573
- SMILESCCC(C)C(C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NC(CCSC)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CC(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)N
StoringandUsingYourProduct
- Solubilityoverviewsolubleinwater
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCaMKinaseII(290-309),CalmodulinAntagonist
Calcium/calmodulin-dependentproteinkinaseII.Characterizationofdistinctcalmodulinbindingandinhibitorydomains.
PayneMEetal(1988)JBiolChem263(15):7190-5.PubMedID:2835367MutationalanalysisofCa(2+)-independentautophosphorylationofcalcium/calmodulin-dependentproteinkinaseII.
MukherjiSetal(1995)JBiolChem270(23):14062-7.PubMedID:7775466Characteristicsoftheinhibitoryeffectofcalmodulinonspecific[125i]omega-conotoxinGVIAbindingtocrudemembranesfromchickbrain.
IchidaSetal(2000)NeuRochemRes25(12):1629-35.PubMedID:11152392
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
