你好Bio/bpV（bipy）/HB0144/25mg
商品编号：
HB0144-25mg
品牌：
hellobio
市场价：
¥6435.00
美元价：
4950.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NamebpV(bipy)
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Short descriptionPotent protein PTP inhibitor
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Biological descriptionPotent protein phosphotyrosine phosphatase (PTP) inhibitor (IC50 values are 18 and 164 nM for PTP-β and PTP-1B respectively). Also inhibits phosphatase and tensin homologue (PTEN) (IC50 = 18 nM). Displays insulin-mimetic properties.
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Biological actionInhibitor
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Purity>95%
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Our products in actionSubmit Your Citation Now
Properties
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Chemical namePotassiumbisperoxo(bipyridine)oxovanadate(V)
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Molecular Weight326.2
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Chemical structure
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Molecular FormulaK[VO(O2)2C10H8N2]
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CAS Number127393-89-9
Storing and Using Your Product
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Storage instructions+4°C
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Solubility overviewsoluble in water
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for bpV(bipy)
Inhibition Effects of Some Bioactive Peroxovanadium Complexes on the Tyrosine Phosphatase.
Zhou XW et al (2000) Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 32(2) : 133-138.PubMedID: 12098789Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics.
Posner BI et al (1994) J Biol Chem 269(6) : 4596-604.PubMedID: 8308031Bisperoxovanadium compounds are potent PTEN inhibitors.
Schmid AC et al (2004) FEBS Lett 566(1-3) : 35-8.PubMedID: 15147864Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen).
Band CJ et al (1997) Mol Endocrinol 11(13) : 1899-910.PubMedID: 9415395
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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