你好Bio/Benidipine盐酸盐/HB1216/100mg
商品编号：
HB1216-100mg
品牌：
hellobio
市场价：
¥4914.00
美元价：
3780.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameBenidipinehydrochloride
- ShortdescriptionCa2+channelinhibitor
- BIOLOGicaldescriptionL-,N-andT-typeCa2+channelinhibitor(IC50=2.7nMforICainhibition).Inhibitstheactivationofaldosterone-inducedmineralocorticoidreceptor.Showsanti-atherosclerotic,antihypertensiveandcardioprotectiveactions.
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(4R)-rel-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid3-methyl5-[(3R)-1-(phenylmethyl)-3-piperidinyl]esterhydrochloride
- MolecularWeight542.02
- Chemicalstructure
![Benidipine hydrochloride [91599-74-5]](images/hellobio/201710/hb1216.png "Benidipine hydrochloride [91599-74-5]")
- MolecularFormulaC28H31N3O6.HCl
- CASNumber91599-74-5
StoringandUsingYourProduct
- Storageinstructionsroomtemperature(desiccate)
- SolubilityoverviewsolubleinDMSO(75mM)orethanol(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforBenidipinehydrochloride
Mechanismsoflong-lastingeffectsofbenidipineonCacurrentinguinea-pigventricularcells.
YamamotoMetal(1990)BrJPharmacol100(4):669-76.PubMedID:2169935Pharmacological,pharmacokinetic,andclinicalpropertiesofbenidipinehydrochloride,anovel,long-actingcalciumchannelblocker.
YaoKetal(2006)JPharmacolSci100(4):243-61.PubMedID:16565579TheL-,N-,andT-typetriplecalciumchannelblockerbenidipineactsasanantagoNISTofmineralocorticoidreceptor,amemberofnuclearreceptorfamily.
KosakaHetal(2010)EurJPharmacol635(1-3):49-55.PubMedID:20307534
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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