Hello Bio/5-Azacytidine/HB1374/
市场价：
¥585.00
美元价：
450.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name5-Azacytidine
- ShortdescriptionDNAmethyltransferaseinhibitor.Improvesstemcellreprogrammingefficiency.
- BIOLOGicaldescriptionDNAmethyltransferaseinhibitor.Causeshypomethylation.InhibitsWnt-β-cateninsignalingpathwayandimprovesstemcellreprogrammingefficiency.Showsanti-viral,anti-proliferativeandanti-canceractions.
- Alternativenames5-AzadCyD;NSC102816;azaCyd;5-AZC
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
- MolecularWeight244.2
- Chemicalstructure
![5-Azacytidine [320-67-2]](images/hellobio/201710/hb1374.png "5-Azacytidine [320-67-2]")
- MolecularFormulaC8H12N4O5
- CASNumber320-67-2
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- Solubilityoverviewsolubleinwater(50mM)orDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor5-Azacytidine
5-AzacytidinesuppressestheproliferationofpancreaticcancercellsbyinhibitingtheWnt/β-cateninsignalingpathway.
ZhangHetal(2014)GenetMolRes13(3):5064-72.PubMedID:250617315-azacytidinereducesmethylation,promotesdifferentiationandinducestumorregressioninapatient-derivedIDH1mutantgliomaxenograft.
BorodovskyAetal(2013)Oncotarget4(10):1737-47.PubMedID:240778055-Azacytidinecaninducelethalmutagenesisinhumanimmunodeficiencyvirustype1.
DappMJetal(2009)JVirol83(22):11950-8.PubMedID:19726509
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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