你好Bio/L-抗坏血酸/HB1238/25g
商品编号：
HB1238-25g
品牌：
hellobio
市场价：
¥273.00
美元价：
210.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameL-Ascorbicacid
- ShortdescriptionAntioxidant.EnhancesiPSCgenerationandincreasesreprogrammingefficiency.
- BIOLOGicaldescription
Naturallyoccurringantioxidant.
EnhancesiPSCgenerationandincreasesreprogrammingefficiency.Alsosupportsmesenchymalstemcellproliferationandpromotesdifferentiationofosteoblastsfromhuman/mouseMSCsandmESCs.
AlsoaCav3.2channelinhibitor(IC50=6.5µM)whichexhibitslittleornoactivityatCav3.1andCav3.3channels.Commonlyusedwithdexamethasoneand β-Glyforosteogenicdifferentiationofstemcells.
- AlternativenamesL-Ascorbate
- BiologicalactionActivator
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname3-Oxo-L-gulofuranolactone
- MolecularWeight176.12
- Chemicalstructure
![L-Ascorbic acid [50-81-7]](images/hellobio/201710/hb1238.png "L-Ascorbic acid [50-81-7]")
- MolecularFormulaC6H8O6
- CASNumber50-81-7
- PubChemidentifier54670067
- SMILESC([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O
- InChiInChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h4,5,7-10H,1H2/t2-,5+/m0/s1
- InChiKeyCIWBSHSKHKDKBQ-JLAZNSOCSA-N
- MDLnumberMFCD00064328
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinwater(500mM)andinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforL-Ascorbicacid
Molecularmechanismsofsubtype-specificinhibitionofneuronalT-typecalciumchannelsbyascorbate.
NelsonMTetal(2007)JNeurosci27(46):12577-83.PubMedID:18003836VitaminCasanantioxidant:evaluationofitsroleindiseaseprevention.
PadayattySJetal(2003)JAmCollNutr22(1):18-35.PubMedID:12569111Protectiveactionofananti-oxidant(L-Ascorbicacid)againstgenotoxicityandcytotoxicityinmiceduringp-DAB-inducedhepatocarcinogenesis.
SurjyoBetal(2004)IndianJCancer41(2):72-80.PubMedID:15318012
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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