你好生物/青蒿素/HB1115/1g
市场价：
¥6727.50
美元价：
5175.00
产品分类：
酸碱缓冲液
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3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameArtemisinin
- ShortdescriptionPlasmodiumfalciparumSERCAorthologueinhibitor
- BIOLOGicaldescriptionPlasmodiumfalciparumSERCAorthologue(PfATP6)inhibitor(Ki=150nM).ThoughttogeneratecytotoxicC-rADIcals.Showsanti-malarial,anti-proliferativeandanti-neoplasticactions.
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one
- MolecularWeight282.33
- Chemicalstructure
![Artemisinin [63968-64-9]](images/hellobio/201710/hb1115.png "Artemisinin [63968-64-9]")
- MolecularFormulaC15H22O5
- CASNumber63968-64-9
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(75mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforArtemisinin
ArtemisininstargettheSERCAofPlasmodiumfalciparum.
Eckstein-LudwigUetal(2003)Nature424(6951):957-61.PubMedID:12931192ArtemisinininhibitsneuroblastomaproliferationthroughactivationofAHP-activatedproteinkinase(AMPK)signaling.
TanWQetal(2014)Pharmazie69(6):468-72.PubMedID:24974584Considerationsonthemechanismofactionofartemisininantimalarials:part1--the"carbonradical"and"heme"hypotheses.
HaynesRKetal(2013)InfectDisordDrugTargets13(4):217-77.PubMedID:24304352
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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