Hello Bio/Arcaine sulfate/HB0118/
市场价：
¥721.50
美元价：
555.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameArcaine sulfate
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Short descriptionCompetitive NMDA receptor antagonist / NOS inhibitor
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Biological descriptionCompetitive NMDA receptor antagonist. Binds at the polyamine site. Also a NOS (Nitric oxide synthase) inhibitor. Reduces NMDA single-channel currents in a voltage-dependent manner.
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Biological actionAntagonist
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Purity>99%
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Properties
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Chemical nameN,N'-1,4-Butanediylbisguanidine sulfate
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Molecular Weight270.31
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Chemical structure
![Arcaine sulfate [14923-17-2]](images/hellobio/201710/hb0118.png "Arcaine sulfate [14923-17-2]")
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Molecular FormulaC6H16N6.H2SO4
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CAS Number14923-17-2
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PubChem identifier119020
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SMILESC(CCN=C(N)N)CN=C(N)N.OS(=O)(=O)O
Storing and Using Your Product
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Storage instructionsroom temperature
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Solubility overviewsoluble in water (25mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Arcaine sulfate
Structure-activity relationships of arginine analogues on nitric oxide synthase activity in the rat brain.
Yokoi I et al (1994) Neuropharmacology 33(11) : 1261-5.PubMedID: 7532812Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor.
Reynolds IJ (1990) Eur J Pharmacol 177(3) : 215-6.PubMedID: 2155812Investigation of the actions and antagonist activity of some polyamine analogues in vivo.
Doyle KM et al (1998) Br J Pharmacol 124(2) : 386-90.PubMedID: 9641557Spermine and arcaine block and permeate N-methyl-D-aspartate receptor channels.
Araneda RC et al (1999) Biophys J 76(6) : 2899-911.PubMedID: 10354418
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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