Hello Bio/Arcaine sulfate/HB0118/50mg
商品编号：
HB0118-50mg
品牌：
hellobio
市场价：
¥819.00
美元价：
630.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameArcainesulfate
- ShortdescriptionCompetitiveNMDAreceptorantagoNIST/NOSinhibitor
- BIOLOGicaldescriptionCompetitiveNMDAreceptorantagonist.Bindsatthepolyaminesite.AlsoaNOS(Nitricoxidesynthase)inhibitor.ReducesNMDAsingle-channelcurrentsinavoltage-dependentmanner.
- BiologicalactionAntagonist
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameN,N"-1,4-Butanediylbisguanidinesulfate
- MolecularWeight270.31
- Chemicalstructure
![Arcaine sulfate [14923-17-2]](images/hellobio/201710/hb0118.png "Arcaine sulfate [14923-17-2]")
- MolecularFormulaC6H16N6.H2SO4
- CASNumber14923-17-2
- PubChemidentifier119020
- SMILESC(CCN=C(N)N)CN=C(N)N.OS(=O)(=O)O
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- Solubilityoverviewsolubleinwater(25mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforArcainesulfate
Structure-activityrelationshipsofarginineanaloguesonnitricoxidesynthaseactivityintheratbrain.
YokoiIetal(1994)Neuropharmacology33(11):1261-5.PubMedID:7532812ArcaineisacompetitiveantagonistofthepolyaminesiteontheNMDAreceptor.
ReynoldsIJ(1990)EurJPharmacol177(3):215-6.PubMedID:2155812Investigationoftheactionsandantagonistactivityofsomepolyamineanaloguesinvivo.
DoyleKMetal(1998)BrJPharmacol124(2):386-90.PubMedID:9641557SpermineandarcaineblockandpermeateN-methyl-D-aspartatereceptorchannels.
AranedaRCetal(1999)BiophysJ76(6):2899-911.PubMedID:10354418
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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