Hello Bio/AR-A 014418/HB1258/50mg
商品编号：
HB1258-50mg
品牌：
hellobio
市场价：
¥6552.00
美元价：
5040.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameAR-A014418
- ShortdescriptionPotent,selectiveGSK3inhibitor
- BIOLOGicaldescriptionPotentandselectiveGSK3inhibitor(IC50=104nM)whichactscompetitively.Exhibitslittleactivityforcdk2andcdk5(IC50valuesare>100µM).Alsoinhibitstauphosphorylation(IC50=2.7µM).
- BiologicalactionInhibitor
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameN-[(4-Methoxyphenyl)methyl]-N"-(5-nitro-2-thiazolyl)urea
- MolecularWeight308.31
- Chemicalstructure
![AR-A 014418 [487021-52-3]](images/hellobio/201710/hb1258.png "AR-A 014418 [487021-52-3]")
- MolecularFormulaC12H12N4O4S
- CASNumber487021-52-3
StoringandUsingYourProduct
- Storageinstructions+4°C
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(5mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforAR-A014418
Structuralinsightsandbiologicaleffectsofglycogensynthasekinase3-specificinhibitorAR-A014418.
BhatRetal(2003)JBiolChem278(46):45937-45.PubMedID:12928438AR-A014418UsedagainstGSK3betaDownregulatesExpressionofhnRNPA1andSF2/ASFSplicingFactors.
YadavAKetal(2014)JOncol2014:695325PubMedID:24550987
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
联络我们
