Hello Bio/Apigenin/HB0117/100mg
商品编号：
HB0117-100mg
品牌：
hellobio
市场价：
¥4036.50
美元价：
3105.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameApigenin
- ShortdescriptionPKCinhibitor
- BIOLOGicaldescriptionProteinkinaseC(PKC)inhibitorthatcompeteswithATP(IC50=30µMforproteinkinaseCK2).Promotescellcyclearrestandapoptosis.Displaysantioxidant,anticarcinogenicandanti-inflammatoryproperties.Anaturallyoccurringplantflavone.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname4′,5,7-Trihydroxyflavone
- MolecularWeight270.3
- Chemicalstructure
![Apigenin [520-36-5]](images/hellobio/201710/hb0117.png "Apigenin [520-36-5]")
- MolecularFormulaC15H10O5
- CASNumber520-36-5
- PubChemidentifier5280443
- SMILESC1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
StoringandUsingYourProduct
- StorageinstructionsStoreat+4°C
- SolubilityoverviewsolubleinDMSO(27mg/ml)orKOH(50mg/ml,1MKOH)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforApigenin
Apigeninandcancerchemoprevention:progress,potentialandpromise(review).
PatelDetal(2007)IntJOncol30(1):233-45.PubMedID:17143534Moleculartargetsforapigenin-inducedcellcyclearrestandapoptosisinprostatecancercellxenograft.
ShuklaSetal(2006)MolCancerTher5(4):843-52.PubMedID:16648554SuppressionofproteinkinaseCandnuclearoncogeneexpressionaspossIBLemolecularmechanismsofcancerchemopreventionbyapigeninandcurcumin.
LinJKetal(1997)JCellBiochemSuppl28-29:39-48.PubMedID:9589348InhibitionofproteinkinaseCK2preventstheprogressionofglomerulonephritis.
YamadaMetal(2005)ProcNatlAcadSciUSA102(21):7736-41.PubMedID:15897466
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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