Hello Bio/Apicidin/HB1384/5mg
商品编号：
HB1384-5mg
品牌：
hellobio
市场价：
¥5382.00
美元价：
4140.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameApicidin
- ShortdescriptionPotentHDACinhibitor
- BIOLOGicaldescriptionPotenthistonedeacetylase(HDAC)inhibitor(IC50=5nM).Showsanti-protozoal,anti-angiogenic,anti-proliferativeandanti-canceractions.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameCyclo[(2S)-2-Amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]
- MolecularWeight623.78
- Chemicalstructure
![Apicidin [183506-66-3]](images/hellobio/201710/hb1384.png "Apicidin [183506-66-3]")
- MolecularFormulaC34H49N5O6
- CASNumber183506-66-3
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewsolubleinDMSO(2mM)orethanol(2mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforApicidin
Apicidin,ahistonedeacetylaseinhibitor,inhibitsproliferationoftumorcellsviainductionofp21WAF1/Cip1andgelsolin.
HanJWetal(2000)CancerRes60(21):6068-74.PubMedID:11085529Apicidin:anovelantiprotozoalagentthatinhibitsparasitehistonedeacetylase.
Darkin-RattraySJetal(1996)ProcNatlAcadSciUSA93(23):13143-7.PubMedID:8917558Apicidinisahistonedeacetylaseinhibitorwithanti-invasiveandanti-angiogenicpotentials.
KimSHetal(2004)BiochemBiophysResCommun315(4):964-70.PubMedID:14985106
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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