Hello Bio/Apamin/HB1051/2.5mg
商品编号：
HB1051-2.5mg
品牌：
hellobio
市场价：
¥6571.50
美元价：
5055.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameApamin
- ShortdescriptionPotent,selectiveKCa2channelsubfamilyinhibitor
- BIOLOGicaldescriptionPotent,selectiveKCa2channelsubfamilyinhibitor(IC50valuesare3.3nMand83pMforhKCa2.1andrKCa2.2channelsrespectively).FoundinthevenomofApismelliferabee.Bloodbrainbarrierpermeable.Displaysanti-inflammatoryproperties.
- BiologicalactionInhibitor
- OurproductsinactionSubmitYourCitationNow
Properties
- MolecularWeight2027.34
- MolecularFormulaC79H131N31O24S4
- CASNumber24345-16-2
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- Solubilityoverviewsolubleinwater(1mg/ml)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforApamin
Pharmacologicalcharacterizationofsmall-conductanceCa(2+)-activatedK(+)channelsstablyexpressedinHEK293cells.
StrøbaekDetal(2000)BrJPharmacol129(5):991-9.PubMedID:10696100Behavioraleffectsofapamin,aselectiveinhibitoroftheSK(Ca)-channel,inmiceandrats.
vanderStaayFJetal(1999)NeurosciBiobehavRev23(8):1087-110.PubMedID:10643819TheProtectiveEffectofApaminonLPS/Fat-InducedAtheroscleroticMice.
KimSJetal(2012)EvidBasedComplementAlternatMed2012:305454PubMedID:22645626Apamin.
HabermannE(1984)PharmacolTher25(2):255-70.PubMedID:6095335
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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