Hello Bio/Anacardic acid/HB1380/10mg
商品编号：
HB1380-10mg
品牌：
hellobio
市场价：
¥1053.00
美元价：
810.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameAnacardicacid
- ShortdescriptionNon-competitiveHATinhibitor
- BIOLOGicaldescriptionNon-competitivehistoneacetyltransferase(HAT)inhibitor.Inhibitsp300/CBPandp300-associatedfactorHATactions(IC50valuesare5and8.5µMrespectively).AlsoinhibitsNF-κB,inducesERstressandautophagy.Showsanti-cancerandanti-inflammatoryactions.
- AlternativenamesAA
- BiologicalactionInhibitor
- Purity>97%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname2-Hydroxy-6-pentadecylbenzoicacid
- MolecularWeight348.52
- Chemicalstructure
![Anacardic acid [16611-84-0]](images/hellobio/201710/hb1380.png "Anacardic acid [16611-84-0]")
- MolecularFormulaC22H36O3
- CASNumber16611-84-0
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(50mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforAnacardicacid
Smallmoleculemodulatorsofhistoneacetyltransferasep300.
BalasubramanyamKetal(2003)JBiolChem278(21):19134-40.PubMedID:12624111Anacardicacid(6-nonadecylsalicylicacid),aninhibitorofhistoneacetyltransferase,suppressesexpressionofnuclearfactor-kappaB-regulatedgeneproductsinvolvedincellsurvival,proliferation,invasion,andinflammationthroughinhibitionofthei
SungBetal(2008)Blood111(10):4880-91.PubMedID:18349320InductionoftheendoplasmicreticulumstressandautophagyinhumanlungcarcinomaA549cellsbyanacardicacid.
SeongYAetal(2014)CellBiochemBiophys68(2):369-77.PubMedID:23955513
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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