Hello Bio/AM 404/HB1174/10mg
商品编号：
HB1174-10mg
品牌：
hellobio
市场价：
¥858.00
美元价：
660.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameAM404
- ShortdescriptionSelective,competitivecarrier-mediatedanandamidetransportinhibitor
- BIOLOGicaldescriptionSelectiveandcompetitivecarrier-mediatedanandamidetransportinhibitor(IC50=1µM).Activatesvanilloidreceptors.Showsvasodilator,neuroprotectiveandanxiolyticactionsmediatedby5-HT1Areceptors.
- BiologicalactionInhibitor
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameN-(4-Hydroxyphenyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
- MolecularWeight395.58
- Chemicalstructure
![AM 404 [198022-70-7]](images/hellobio/201710/hb1174.png "AM 404 [198022-70-7]")
- MolecularFormulaC26H37NO2
- CASNumber198022-70-7
StoringandUsingYourProduct
- Storageinstructions-20°C
- Solubilityoverviewsolubleinethanol(50mM)orDMSO(50mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforAM404
Delta9-tetrahydrocannABInol(THC)andAM404protectagainstcerebralischaemiaingerbilsthroughamechanisminvolvingcannabinoidandopioidreceptors.
ZaniAetal(2007)BrJPharmacol152(8):1301-11.PubMedID:179657465-HT1AreceptorsareinvolvedintheanxiolyticeffectofDelta9-tetrahydrocannabinolandAM404,theanandamidetransportinhibitor,inSprague-Dawleyrats.
BraidaDetal(2007)EurJPharmacol555(2-3):156-63.PubMedID:17116299TheanandamidetransportinhibitorAM404activatesvanilloidreceptors.
ZygmuntPMetal(2000)EurJPharmacol396(1):39-42.PubMedID:10822052Mechanismsofendocannabinoidinactivation:biochemistryandpharmacology.
GiuffridaAetal(2001)JPharmacolExpTher298(1):7-14.PubMedID:11408519
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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