Hello Bio/Veratridine/HB1006/
市场价：
¥2320.50
美元价：
1785.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameVeratridine
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Short descriptionNa+ channel activator
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Biological descriptionNa+ channel activator. Binds to active channels and prevents the inactive state. Increases persistent sodium current and intracellular Ca2+. Increases reverse Na+ / Ca2+ exchange current, pump activity and exocytosis. Induces action potentials and extended membrane depolarization.
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Biological actionActivator
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Purity>98%
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Properties
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Chemical name4α,9-Epoxy-3β-veratroyloxy-5β-cevan-4β, 12,14,16β,17,20-hexaol
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Molecular Weight673.79
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Chemical structure
![Veratridine [71-62-5]](images/hellobio/201710/hb1006.png "Veratridine [71-62-5]")
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Molecular FormulaC36H51NO11
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CAS Number71-62-5
Storing and Using Your Product
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Storage instructions-20°C
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Solubility overviewsoluble in DMSO (50mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Veratridine
Effects of veratridine on sodium currents and fluxes.
Ulbricht W (1998) Rev Physiol Biochem Pharmacol 133 : 1-54.PubMedID: 9600010Mechanism of the persistent sodium current activator veratridine-evoked Ca elevation: implication for epilepsy.
Fekete A et al (2009) J Neurochem 111(3) : 745-56.PubMedID: 19719824Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine.
Maroto R et al (1994) Eur J Pharmacol 270(4) : 331-9.PubMedID: 7805782[Involvement of veratridine-induced increase of reverse Na(+)/Ca(2+) exchange current in intracellular Ca(2+) overload and extension of action potential duration in rabbit ventricular myocytes].
Kong LH et al (2012) Sheng Li Xue Bao 64(4) : 433-43.PubMedID: 22907304
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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