Hello Bio/Spermidine hydrochloride/HB0586/100mg
商品编号：
HB0586-100mg
品牌：
hellobio
市场价：
¥819.00
美元价：
630.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameSpermidinehydrochloride
- ShortdescriptionnNOSinhibitor/PTPN2activator
- BIOLOGicaldescriptionNeuronalnitricoxidesynthase(nNOS)inhibitorandproteintyrosinephosphatasenon-receptortype2(PTPN2)activator.AlsobindstheNMDApolyaminemodulatorysite.EnhancesPCRamplificationofDNAandimprovesefficacyofDNAcleavage.Potentialanti-inflammatoryproperties.
- BiologicalactionActivator
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameN-(3-Aminopropyl)-1,4-butanediaminetrihydrochloride
- MolecularWeight254.63
- Chemicalstructure
![Spermidine hydrochloride [334-50-9]](images/hellobio/201710/hb0586.png "Spermidine hydrochloride [334-50-9]")
- MolecularFormulaC7H19N3.3HCl
- CASNumber334-50-9
- PubChemidentifier9539
- SMILESNCCCNCCCCN.Cl.Cl.Cl
StoringandUsingYourProduct
- Storageinstructions+4°C(desiccate)
- Solubilityoverviewsolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforSpermidinehydrochloride
Polyaminesinhibitnitricoxidesynthaseinratcerebellum.
HuJetal(1994)NeurosciLett175(1-2):41-5.PubMedID:7526294SpermidinefacilitatesPCRamplificationoftargetDNA.
WanCYetal(1993)PCRMethodsAppl3(3):208-10.PubMedID:8118404Activationofproteintyrosinephosphatasenon-receptortype2byspermidineexertsanti-inflammatoryeffectsinhumanTHP-1monocytesandinamousemodelofacutecolitis.
MorónBetal(2013)PLoSOne8(9):e73703.PubMedID:24040033Effectsofpolyaminesonthebindingof[3H]MK-801totheN-methyl-D-aspartatereceptor:pharmacologicalevidencefortheexistenceofapolyaminerecognitionsite.
WilliamsKetal(1989)MolPharmacol36(4):575-81.PubMedID:2554112
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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