Hello Bio/Spaglumic acid/HB0585/
市场价：
¥955.50
美元价：
735.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameSpaglumicacid
- ShortdescriptionSelectivemGlu3agoNIST,peptideneurotransmitter
- BIOLOGicaldescriptionSelectivemGlu3receptoragonistandendogenousmammalianpeptideneurotransmitter.Blood-brainbarrierpermeable.Showsanti-allergicactions,potentialanalgesicandneuroprotectiveeffects.Decreasessocialwithdrawalandmotorresponseinmousemodelsofschizophrenia.
- BiologicalactionAgonist
- Purity>96%
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameN-Acetyl-L-aspartyl-L-glutamicacid
- MolecularWeight304.26
- Chemicalstructure
![Spaglumic acid [3106-85-2]](images/hellobio/201710/hb0585.png "Spaglumic acid [3106-85-2]")
- MolecularFormulaC11H16N2O8
- CASNumber3106-85-2
- PubChemidentifier91873144
- SMILESCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O.O
- InChiInChI=1S/C11H16N2O8.H2O/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16;/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21);1H2/t6-,7-;/m0./s1
- InChiKeyLQMRHOYCEMZABM-LEUCUCNGSA-N
- MDLnumberMFCD00076652
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewSolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforSpaglumicacid
N-acetylaspartylglutamateselectivelyactivatesmGluR3receptorsintransfectedcells.
WroblewskaBetal(1997)JNeuRochem69(1):174-81.PubMedID:9202308Comparativeefficacyoftopicalantihistaminesinananimalmodelofearlyphaseallergicconjunctivitis.
Sanchis-MerinoMEetal(2008)ExpEyeRes86(5):791-7.PubMedID:18378229
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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