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商品详细Hello Bio/SKF 97541/HB0954/10mg
Hello Bio/SKF 97541/HB0954/10mg
Hello Bio/SKF 97541/HB0954/10mg
商品编号: HB0954-10mg
品牌: hellobio
市场价: ¥1696.50
美元价: 1305.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Productoverview

  • Name
    SKF97541
  • Shortdescription
    PotentGABABreceptoragoNIST
  • BIOLOGicaldescription
    PotentGABABreceptoragonist.Evokeshyperpolarizationsinseptalneurones(EC50=50nM).Showsantidepressantactions.Blood-brainbarrierpermeable.
  • Biologicalaction
    Agonist
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    3-Aminopropyl(methyl)phosphinicacid
  • MolecularWeight
    137.12
  • Chemicalstructure
    SKF 97541 [127729-35-5]
  • MolecularFormula
    C4H12NO2P
  • CASNumber
    127729-35-5

StoringandUsingYourProduct

  • Storageinstructions
    roomtemperature(desiccate)
  • Solubilityoverview
    solubleinwater(100mM)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforSKF97541

  • Electrophysiologicalcharacterizationofpotentagonistsandantagonistsatpre-andpostsynapticGABABreceptorsonneuronesinratbrainslices.

    SeabrookGRetal(1990)BrJPharmacol101(4):949-57.
    PubMedID:1964824
  • ElectrophysiologicalactionsofGABABagonistsandantagonistsinratdorso-lateralseptalneuronesinvitro.

    BonCetal(1996)BrJPharmacol118(4):961-7.
    PubMedID:8799569
  • EffectsofGABABreceptorligandsinanimaltestsofdepressionandanxiety.

    FrankowskaMetal(2007)PharmacolRep59(6):645-55.
    PubMedID:18195453
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.