Hello Bio/D-Serine/HB0267/1g
市场价：
¥448.50
美元价：
345.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameD-Serine
- ShortdescriptionNMDAreceptorco-agoNIST
- BIOLOGicaldescriptionEndogenousNMDAreceptorco-agonist.Bindsattheglycinesitewithhigherpotencythanglycine.InducesCa2+-dependentinactivationofGluN2Asubunit-containingNMDAreceptorswithpotentialneuroprotectiveeffects.
- BiologicalactionAgonist
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(R)-2-amino-3-hydroxypropanoicacid
- MolecularWeight105.09
- Chemicalstructure
![D-Serine [312-84-5]](images/hellobio/201710/hb0267.png "D-Serine [312-84-5]")
- MolecularFormulaC3H7NO3
- CASNumber312-84-5
- PubChemidentifier71077
- SMILESC([C@H](C(=O)O)N)O
- InChiInChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h4,5H,1,4H2,(H,6,7)/t2-/m1/s1
- InChiKeyMTCFGRXMJLQNBG-UWTATZPHSA-N
- MDLnumberMFCD00004269
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinwater(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforD-Serine
D-aminoacidsinthebrain:D-serineinneurotransmissionandneurodegeneration.
WoloskerHetal(2008)FEBSJ275(14):3514-26.PubMedID:18564180D-Serine-inducedInactivationofNMDAReceptorsinCulturedRatHippocampalNeuronsExpressingNR2ASubunitsisCa(2+)-Dependent.
LiXetal(2014)CNSNeurosciTher20(11):951-60.PubMedID:25042179Long-termpotentiationdependsonreleaseofD-serinefromastrocytes.
HenNEBergerCetal(2010)Nature463(7278):232-6.PubMedID:20075918
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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